1 2 3 4 Iberiotoxin - sensitive and - insensitive BK currents in Purkinje neuron
نویسندگان
چکیده
Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somata 5 6 Mark D. Benton, Amanda H. Lewis, Jason S. Bant, and Indira M. Raman 7 Interdepartmental Neuroscience Program, 8 Interdepartmental Biological Sciences Program, and 9 Department of Neurobiology 10 Northwestern University, 11 Evanston, IL USA 12 13 14 15 16 Word counts: 17 Abstract 248 18 Introduction 476 19 Discussion 1851 20 Figure count: 7 21 22 Running title: BK currents in Purkinje somata 23 24 Experimental contributions: MDB, AHL, JSB, & IMR designed, analyzed, and interpreted 25 experiments; MDB, AHL, and JSB conducted the experiments; IMR wrote the manuscript 26 27 Address for Correspondence: 28 Indira M. Raman 29 Department of Neurobiology 3
منابع مشابه
Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somata.
Purkinje cells have specialized intrinsic ionic conductances that generate high-frequency action potentials. Disruptions of their Ca or Ca-activated K (KCa) currents correlate with altered firing patterns in vitro and impaired motor behavior in vivo. To examine the properties of somatic KCa currents, we recorded voltage-clamped KCa currents in Purkinje cell bodies isolated from postnatal day 17...
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